Guillermo Tellez-Isaias

Bird flu’s growing impact calls for urgent action at international summit

By Jenifer Fouch
University of Arkansas System Division of Agriculture
Arkansas Agricultural Experiment Station

FAYETTEVILLE, Ark. — As highly pathogenic avian influenza continues to infect more than just birds, scientists and industry professionals want to prevent it from infecting more species and continuing to impact animal and human health, the environment and the economy.

CLUCKING UP SOLUTIONS — Guillermo Tellez-Isaias, the chairman of the summit leads opening remarks at the 2024 Internaional Avian Influenza Summit. (U of A System Division of Ag photo)

The four-day International Avian Influenza and One Health Emerging Issues Summit hosted by the Center of Excellence for Poultry Science had a total of 1,270 registered participants from 51 countries, in-person and virtually, to share and learn more about HPAI, or highly pathogenic avian influenza, and other diseases impacting animals and humans.

Guillermo Tellez-Isaias, the chairman of the summit and retired research professor for the Center of Excellence for Poultry Science and the Arkansas Agricultural Experiment Station, says there are other threats to animal and human health in addition to the bird flu.

"The highly pathogenic avian influenza virus has naturally been able to adapt to species that it never infected before. If it fully adapts to humans, COVID-19 will look like a small cold compared to what this virus could cause," Tellez-Isaias said, comparing its threat to the Spanish flu in 1918. "So, that's why we wanted to have this summit, to create awareness for people worldwide."

Tellez-Isaias said participants at the summit will produce a document with guidelines and recommendations for national and international health authorities, based on group discussions and expert presentations, to help guide future efforts in combating highly pathogenic avian influenza and other emerging health threats.

The Center of Excellence for Poultry Science is part of the University of Arkansas System Division of Agriculture and the University of Arkansas Dale Bumpers College of Agricultural, Food and Life Sciences. The center performs the three land grant missions of teaching — carried out through Bumpers College — and research and extension through the Division of Agriculture’s Arkansas Agricultural Experiment Station and Cooperative Extension Service.

After a successful inaugural event in 2023, Tellez-Isaias said, organizers expanded the scope in the second year to include other emerging issues affecting cattle, swine, bees, humans and more as part of the One Health concept, which emphasizes that animal, human and environmental health are all interconnected.

"The first two days, we focused on highly pathogenic avian influenza, but not only in poultry. We extended it to wild and commercial animals, including dairy," Tellez-Isaias said. "And we discussed avian influenza and other diseases, including exotic diseases like the African swine fever, which is already in our backyard in the Dominican Republic. It's something we are keeping an eye on."

Urgency of collaboration

Tellez-Isaias says it's urgent to focus on these diseases globally, as bird flu has spread to different species in all continents including  Antarctica.

"These diseases know no borders," he said.

Members of industry, governmental and regulatory agencies, and scientists from around the world presented their work at the summit. Tellez-Isaias said their findings could improve animal health overall and potentially contribute to minimizing the impacts of bird flu and other viruses.

From the Division of Agriculture, Sami Dridi, professor of poultry science, talked about poultry production sustainability, specifically heat stress challenges and potential mechanism-based strategies. Dridi's research includes working with chickens bred to conserve water while maintaining growth under heat stress. He found that water efficiency is improving with each new generation and has the potential to expand with application to other poultry operations, such as turkeys and ducks.

Tomi Obe, assistant professor with the Center of Excellence for Poultry Science and the poultry science department, presented research on pre- and post-harvest strategies for salmonella control in poultry production. She discussed different methods to consider at feed mills, farms and the processors. Obe is also part of the Arkansas Center for Food Safety within the food science department.

PROTECTING POULTRY — Jada Thompson, assistant professor of agricultural economics and agribusiness with the Arkansas Agricultural Experiment Station, gave an overview of how highly pathogenic avian influenza affected egg prices and resulted in other economic impacts. (U of A System Division of Ag photo)

Jada Thompson, assistant professor in the agricultural economics and agribusiness department, talked about the economic impacts of highly pathogenic avian influenza, including how the disease impacts producers and consumers.  

Bill Potter, associate professor and extension poultry specialist with the Division of Agriculture, discussed One Health strategies to optimize poultry intestinal integrity and pre-harvest food safety. He discussed proposed regulations around salmonella and shared research showing the efficacy of implementing vaccines in poultry.

Adnan Alrubaye, assistant professor of poultry science, talked about management practices to mitigate lameness in broiler chickens caused by specific bacteria.

Those attending the summit included both international and local researchers, veterinarians and private sector professionals.  

Amanda Bray, a poultry science alumna and co-owner of Northwest Arkansas Veterinary Services in Springdale, said staying informed on industry trends domestically and internationally helps her learn what services to offer.

"Our primary focus is the poultry and dairy industries,” Bray said. “And [bird flu] is a very big problem. So, the more knowledge I have, the better I know how to support others in the industry and what tests we need to develop and offer."

United front for global health

Liliana Monroy is founder and CEO of Natural Animal Health, a company providing gut health products to producers. Monroy said she has garnered a long-trusting relationship with researchers with the Division of Agriculture, and that “collaboration is vital” to fight highly pathogenic avian influenza.

"If you want to be successful, you have to go to the people who know more,” Monroy said. “And you need to work very closely with professors and researchers. We cannot work in silos. Since we come from different backgrounds, we need to unite efforts with doctors, environmental entities, leaders in the private sector, and so on, to stop what's going on."

Monroy, who also presented during the conference, says biosecurity protocols, although crucial to preventing the spread of bird flu, have also created many roadblocks for businesses and producers.

The International Avian Influenza Summit was hosted by the University of Arkansas System Division of Agriculture, the Dale Bumpers College of Agricultural, Food and Life Sciences, and the Center of Excellence for Poultry Science. The American College of Poultry Veterinarians and the American Veterinary Medical Association approved the conference for continuing education credits with 23 and 26 CE credits respectively and the Professional Animal Auditor Certification Organization with 12 CE credits. The event was held at the Don Tyson Center for Agricultural Sciences in Fayetteville, Sept. 30 through Oct. 3.

To learn more about the Division of Agriculture research, visit the Arkansas Agricultural Experiment Station website. Follow us on X at @ArkAgResearch, subscribe to the Food, Farms and Forests podcast and sign up for our monthly newsletter, the Arkansas Agricultural Research Report. To learn more about the Division of Agriculture, visit uada.edu. Follow us on X at @AgInArk. To learn about extension programs in Arkansas, contact your local Cooperative Extension Service agent or visit uaex.uada.edu.

International Avian Influenza and One Health Emerging Issues Summit set for fall 2024

By John Lovett
University of Arkansas System Division of Agriculture
Arkansas Agricultural Experiment Station

FAYETTEVILLE, Ark. — As highly pathogenic avian influenza viruses adapt to infect a broad range of species, including one recent human case, the Center of Excellence for Poultry Science has expanded the outlook for its second annual international conference.

AVIAN FLU SUMMIT — Highly pathogenic avian influenza has adapted to species other than poultry, prompting The Internatioanl Avian Influenza and One Health Emerging Issues Summit this fall in Fayetteville. (U of A System Division of Agriculture photo)

The International Avian Influenza and One Health Emerging Issues Summit will be held in person and online, Sept. 30-Oct. 3, at the Don Tyson Center for Agricultural Sciences, 1371 W. Altheimer Dr., in Fayetteville.

“Avian influenza has adapted to mammalian species, and it is now endemic in the United States,” said Guillermo Tellez-Isaias, poultry science research professor for the Arkansas Agricultural Experiment Station, the research arm of the University of Arkansas System Division of Agriculture. “Now we see that migratory birds that were not susceptible in the past are dying, and wild birds are spreading the virus worldwide.”

Tellez-Isaias is one of 14 organizers for the summit, hosted by the Division of Agriculture and the University of Arkansas Dale Bumpers College of Agricultural, Food and Life Sciences. Last year, 23 speakers made presentations over two days, and 1,842 people registered from 81 countries. This year, the summit remains free and will have 46 speakers over four days.

“The One Health concept recognizes that everything that affects humans will impact animals and the environment,” Tellez-Isaias said. “We are all connected in this world.”

Expanded outlook

Knowing the virus could mutate, organizers of the summit had already expanded the outlook to include other species and emerging diseases prior to the March 25 outbreak of H5N1 highly pathogenic avian influenza, or HPAI, in dairy cows.

On April 1, the Centers for Disease Control and Prevention announced it confirmed one human HPAI infection after exposure to dairy cattle in Texas. The CDC has also reported H5N1 in domestic cats in Kansas and Texas, which “reflects the continued spread of clade 2.3.4.4b viruses that entered the country in late 2021.”

The CDC’s risk assessment for the public remains “low.” However, like the virus that is thought to have originated in a Kansas army camp near the end of World War I and became known as the “Spanish flu,” HPAI viruses mutate and have the potential to inflict massive casualties.

Tellez-Isaias said H5N1 “hijacks the immune system and creates a tremendous inflammatory response like an anaphylactic shock” in its victims.

“That’s why you don’t see any clinical signs,” Tellez-Isaias said. “No respiratory, sneezy coughing, no lesions. Nothing. You can leave a poultry house, and everything seems fine, but when you come back in the morning, you have up to 100 percent mortality.”

Since January 2022, multiple HPAI viruses have infected millions of wild birds, commercial poultry flocks and more than two dozen species of terrestrial and marine mammals worldwide. This bird flu has also spread across Africa, Asia, the Americas, Australia, Europe and Antarctica.

Emerging issues

Salmonella Infantis, Salmonella Gallinarum, Inclusion Body Hepatitis, and Histomonas meleagridis, a protozoal parasite that causes histomonosis, will also be addressed by speakers as emerging issues in food production.

Histomonosis, also known as blackhead disease, is lethal in turkeys 12 to 14 weeks old. It was controlled by arsenic-based drugs in poultry feed from the 1940s to 2013, when the U.S. Food and Drug Administration withdrew approval for three common formulas. The FDA removed another chemical formula from the market in 2015. There are currently no vaccinations to control histomonosis.

Event registration

To register for the summit, online or in-person, please click on “Registration” at the top of the event page. The capacity for in-person attendees is 150 people.

To learn more about Division of Agriculture research, visit the Arkansas Agricultural Experiment Station website: https://aaes.uada.edu. Follow on Twitter at @ArkAgResearch. To learn more about the Division of Agriculture, visit https://uada.edu/. Follow us on Twitter at @AgInArk. To learn about extension programs in Arkansas, contact your local Cooperative Extension Service agent or visit www.uaex.uada.edu.